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Invitrogen
PGAM2 Polyclonal Antibody
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PGAM2 Antibody (PA5-115744) in IHC (P)
Immunohistochemistry analysis of PGAM2 in human liver cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115744) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115744
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PGAM2(Accession P15259), corresponding to amino acid residues P124-Q174.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total PGAM2.
靶标信息
Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM2 encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; PGAM-M; Phosphoglycerate mutase 2; Phosphoglycerate mutase isozyme M; phosphoglycerate mutase muscle-specific subunit
基因别名: D14Mgh1; PGAM-M; PGAM2; PGAMM; Pgmut
UniProt ID: (Mouse) O70250, (Rat) P16290
Entrez Gene ID: (Mouse) 56012, (Rat) 24959
catalytic activity
bisphosphoglycerate mutase activity
bisphosphoglycerate 2-phosphatase activity
phosphoglycerate mutase activity
protein binding
hydrolase activity
isomerase activity
intramolecular transferase activity, phosphotransferases
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
cofactor binding
mutase
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