Search
Search
Fabgennix
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide, which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ANP-B; ANPR-B; ANPRB; atrial natriuretic peptide B-type receptor; atrial natriuretic peptide receptor B; atrial natriuretic peptide receptor type B; GC-B receptor; guanylate cyclase (EC 4.6.1.2); guanylate cyclase 2B; guanylate cyclase B; guanylyl cyclase B; guanylyl cyclase-B; mNPR-B; natriuretic peptide receptor B type; natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B); natriuretic peptide receptor-B; Nppb receptor; NPR-B; unnamed protein product
基因别名: AMDM; ANPb; ANPRB; cn; ECDM; GC-B; GC-B2; GC-B3; GCB; GUC2B; GUCY2B; mNPR-B; NPR-B; NPRB; NPRBi; pwe; SNSK
UniProt ID: (Human) P20594, (Mouse) Q6VVW5, (Rat) P16067
Entrez Gene ID: (Human) 4882, (Mouse) 230103, (Rat) 116564