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Immunogen sequence: KMVHNGIEYG DMQLICEAYH LMKDVLGMAQ DEMAQAFEDW NKTELDSFLI EITANILKFQ DTDGKHLLPK IRDSAGQKGT GKWTAISALE YGVPVTLIGE AVFARCLSSL KDERIQASKK LKGPQKFQFD GDKKSFLEDI RKALYASKII SYAQGFMLLR QAATEFGWTL NYGGIALMWR GGCIIRSVFL GKIKDAFDRN PELQNLLLDD FFKSAVENCQ DSWRRAVSTG VQAGIPMPCF TTALSFYDGY RHEMLPASLI QAQRDYFGAH TYELLAKPGQ FIHTNWTGHG GTVSSSSYNA; Positive Samples: A-549, 293T, Raji, Mouse kidney, Mouse lung, Mouse spleen, Rat kidney; Cellular Location: Cytoplasm
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 6-phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase, decarboxylating-like
基因别名: 0610042A05Rik; 6PGD; AU019875; C78335; PGD; PGDH
UniProt ID: (Rat) P85968, (Human) P52209, (Mouse) Q9DCD0
Entrez Gene ID: (Rat) 100360180, (Human) 5226, (Mouse) 110208