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Positive Control: Mouse liver tissue lysate, mouse placenta tissue lysate, rat spleen tissue lysate, rat testis tissue lysate, mouse brain tissue lysate, zebrafish tissue lysates, A549, rat spleen tissue, mouse testis tissue.
Subcellular Location: Cytoplasm.
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 6-phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase, decarboxylating-like; phosphogluconate hydrogenase
基因别名: 0610042A05Rik; 6PGD; AU019875; C78335; fi03d03; PGD; PGDH; wu:fi03d03; zgc:111848; zgc:55585
UniProt ID: (Rat) P85968, (Human) P52209, (Mouse) Q9DCD0
Entrez Gene ID: (Rat) 100360180, (Human) 5226, (Mouse) 110208, (Zebrafish) 406762