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Agrisera
PGDH3/Phosphoglycerate dehydrogenase 3 (chloroplastic) Polyclonal Antibody
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PGDH3/Phosphoglycerate dehydrogenase 3 (chloroplastic) Antibody (AS20-4391) in WB
Lane: 1:0.5 mg tissue wild type 2:1 mg tissue wild type 3:1.5 mg tissue wild type 4:2 mg tissue wild type 5:2.5 mg tissue wild type 6:2.5 mg tissue pgdh 3-1 (PGDH 3 knockout) 7:2.5 mg tissue pgdh 3-2 (PGDH 3 knockout) Remaining signal in lanes 6 and 7 is from the other two isoforms of the enzyme that were not knocked out. Arabidopsis thaliana tissue was frozen with liquid nitrogen and ground to a fine powde... View More
产品信息
AS20-4391
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
Recombinant, full-length PGDH3 of Arabidopsis thaliana, overexpressed in E.coli with terminal His-tag.
偶联物
形式
Lyophilized
保存液
whole serum
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana, Nicotiana benthamiana
靶标信息
PGDH3, also called 3 phosphoglycerate dehydrogenase 3, is an enzyme in the phosphorylated serine biosynthesis pathway that diverts 3 phosphoglycerate from glycolysis to produce phosphoserine and ultimately L serine in plants. Serine supports protein synthesis, one carbon metabolism, photorespiration, and redox balance, making PGDH3 important for growth and stress adaptation. PGDH3 catalyzes the NAD dependent oxidation of 3 phosphoglycerate to 3 phosphohydroxypyruvate and often shows condition and tissue specific expression, complementing other PGDH isoforms to meet serine demand during development and under light and abiotic stress. Perturbation of PGDH3 affects serine pools, impacts photorespiratory efficiency, and alters metabolic flexibility and resilience through changes in amino acid and redox homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-phosphoglycerate dehydrogenase; PGDH2; phosphoglycerate dehydrogenase 2
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