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Invitrogen
PGK1/PGK2 Recombinant Rabbit Monoclonal Antibody (HL1775)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-47177
产品规格
种属反应
Human,
Mouse,
Rat,
Zebrafish
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL1775
抗原
Recombinant protein of human PGK1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
靶标信息
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate|The encoded protein may also act as a cofactor for polymerase alpha|Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin|The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions|Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment|Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosyltransferase diphtheria toxin-like 1; ADPRT 1; ARTD1; Carboxypeptidase A1; Casein kinase I isoform alpha; Casein kinase I isoform alpha-like; CASP-1; Caspase-1; CK1; CKI-alpha; CKI-alpha-like; DNA ADP-ribosyltransferase PARP1; HEL-S-68p; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL-1BC; interleukin 1 beta-converting enzyme; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; Microtubule-associated protein tau; MIG10; NAD(+) ADP-ribosyltransferase 1; Neurofibrillary tangle protein; p45; Paired helical filament-tau; PARP-1; PGKA; PHF-tau; phosphoglycerate kinase 1; Poly [ADP-ribose] polymerase 1; Poly[ADP-ribose] synthase 1; Protein poly-ADP-ribosyltransferase PARP1; Tubulin beta-2 chain; Tubulin beta-2C chain; Tubulin beta-4B chain
基因别名: ADPRT; CASP1; CPA; CPA1; CSNK1A1; CSNK1A1L; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; HIST1H3A; HIST1H3B; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; ICE; IL1BC; IL1BCE; MAPT; MAPTL; MTBT1; PARP1; PPOL; TAU; TUBB2C; TUBB4B
UniProt ID: (Mouse) P29452, (Rat) P97633
Entrez Gene ID: (Mouse) 12362, (Rat) 113927
endopeptidase activity
cysteine-type endopeptidase activity
protein binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
scaffold protein binding
magnesium ion binding
glycoprotein binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
peptide binding
phosphoprotein binding
non-receptor serine/threonine protein kinase
protease
response to hypoxia
microglial cell activation
proteolysis
apoptotic process
myoblast fusion
memory
response to bacterium
regulation of autophagy
response to organic cyclic compound
protein processing
response to lipopolysaccharide
interleukin-1 beta production
response to ATP
response to drug
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of circadian sleep/wake cycle, non-REM sleep
positive regulation of cytokine secretion
positive regulation of interleukin-1 alpha secretion
positive regulation of interleukin-1 beta secretion
regulation of inflammatory response
mitochondrial depolarization
membrane hyperpolarization
pyroptosis
cellular response to organic substance
programmed necrotic cell death
toxin transport
cell morphogenesis
protein phosphorylation
phagocytosis
mitotic nuclear division
regulation of cell shape
Wnt signaling pathway
peptidyl-serine phosphorylation
cell division
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