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Invitrogen
PHAP I Polyclonal Antibody
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PHAP I Antibody (PA5-96418) in IHC (P)
Immunohistochemistry analysis of PHAP I in paraffin-embedded human breast cancer using. Samples were incubated with PHAP I Polyclonal antibody (Product # PA5-96418) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-96418
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ANP32A (NP_0062961)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.37 mg/mL
规格
37 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI NVGLTSIANL PKLNKLKKLE LSDNRVSGGL EVLAEKCPNL THLNLSGNKI KDLSTIEPLK KLENLKSLDL FNCEVTNLND YRENVFKLLP QLTYLDGYDR DDKEAPDSDA EGYVEGLDDE; Positive Samples: 293T, HepG2, HL-60, MCF7, Raji, U-251MG, Mouse brain, HT-29; Cellular Location: Cytoplasm, Endoplasmic reticulum, Nucleus
靶标信息
PHAP I is implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acid nuclear phosphoprotein 32 (leucine rich); Acidic leucine-rich nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein 32; acidic nuclear phosphoprotein 32 family, member A; Acidic nuclear phosphoprotein pp32; LANP; Leucine-rich acidic nuclear protein; leucine-rich acidic nuclear protein LANP; MGC119787; MGC150373; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; vacidic (leucine-rich) nuclear phosphoprotein 32 family, member A
基因别名: Anp32; Anp32a; I1PP2A; LANP; PHAP1; pp32; W91701
UniProt ID: (Rat) P49911, (Mouse) O35381
Entrez Gene ID: (Rat) 25379, (Mouse) 11737
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
