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Invitrogen
PHC2 Polyclonal Antibody
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PHC2 Antibody (PA5-89939) in WB
Western blot analysis of PHC2 in extracts of various cell lines. Samples were incubated with PHC2 Polyclonal antibody (Product # PA5-89939) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-89939
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 250-323 of human PHC2 (NP_0044182)
偶联物
形式
Liquid
浓度
1.32 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: HFLPSEPTKW NVEDVYEFIR SLPGCQEIAE EFRAQEIDGQ ALLLLKEDHL MSAMNIKLGP ALKIYARISM LKDS; Positive Samples: DU145, HT-29, HeLa, Jurkat, 293T; Cellular Location: Nucleus
靶标信息
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: early development regulator 2 (homolog of polyhomeotic 2); Early development regulatory protein 2; hPH2; polyhomeotic 2; polyhomeotic-like 2; Polyhomeotic-like protein 2
基因别名: EDR2; HPH2; PH2; PHC2
UniProt ID: (Human) Q8IXK0
Entrez Gene ID: (Human) 1912
