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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PHD2 Antibodies

          Invitrogen

          PHD2 Monoclonal Antibody (366G/76/3)

          高级验证
          查看其他11个PHD2抗体

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          说明书
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          Cite PHD2 Monoclonal Antibody (366G/76/3)

          • 抗体检测数据 (4)
          • 高级验证 (1)
          PHD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          PHD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          图: 1 / 5

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          PHD2 Antibody (MA5-16143) in IHC (P)

          Immunohistochemistry analysis of PHD2 in human renal cancer. Samples were incubated with PHD2 monoclonal antibody (Product # MA5-16143). DAB with hematoxylin counterstain. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          查看产品

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          PHD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PHD2 Antibody in Western Blot (WB)
          PHD2 Antibody in Western Blot (WB)
          PHD2 Antibody in Western Blot (WB)
          PHD2 Antibody
          PHD2 Monoclonal Antibody (366G/76/3)

          产品信息

          MA5-16143

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          0.5-2 µg/mL
          -

          免疫组化(石蜡) (IHC (P))

          1:400
          -
          产品规格

          种属反应

          Human, Mouse, Rat

          宿主/亚型

          Mouse / IgG1

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          366G/76/3

          抗原

          Peptide within residues 1-50 of human PHD2/HIF Prolyl Hydroxylase 2.
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Protein G

          保存液

          TBS

          内含物

          0.05% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11153830

          产品详细信息

          The target sequence has 83% sequence homology with mouse.

          靶标信息

          SYMPK is a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: C1ORF12 antibody; Egl nine homolog 1; egl nine-like protein 1; egl-9 family hypoxia-inducible factor 1; EGLN 1 EGLN1; HIF PH2; HIF prolyl hydroxylase 2; HIF-P4H 2; HIF-PH2; HIF-prolyl hydroxylase 2; Hypoxia-inducible factor prolyl hydroxylase 2; P4H2; PHD2; Prolyl Hy; Prolyl hydroxylase domain-containing protein 2; SM-20; zinc finger MYND domain-containing protein 6

          查看更多 收起

          基因别名: AI503754; C1orf12; ECYT3; EGLN1; HALAH; Hif-p4h-2; HIF-PH2; HIFPH2; HPH-2; HPH2; ORF13; PHD-2; PHD2; PNAS-118; PNAS-137; SM-20; SM20; ZMYND6

          查看更多 收起

          UniProt ID: (Human) Q9GZT9, (Mouse) Q91YE3

          查看更多 收起

          Entrez Gene ID: (Human) 54583, (Mouse) 112405, (Rat) 308913

          查看更多 收起

          功能
          iron ion binding protein binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors enzyme binding L-ascorbic acid binding peptidyl-proline dioxygenase activity peptidyl-proline 4-dioxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen metal ion binding dioxygenase activity
          参与通路
          response to hypoxia peptidyl-proline hydroxylation to 4-hydroxy-L-proline negative regulation of cAMP catabolic process oxygen homeostasis negative regulation of sequence-specific DNA binding transcription factor activity regulation of angiogenesis negative regulation of cyclic-nucleotide phosphodiesterase activity cardiac muscle tissue morphogenesis oxidation-reduction process heart trabecula formation ventricular septum morphogenesis labyrinthine layer development response to nitric oxide regulation of transcription from RNA polymerase II promoter in response to hypoxia
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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