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Invitrogen
PHEX Polyclonal Antibody
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产品信息
PA5-21714
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the Extracellular domain of human PHEX. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.99 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: Molt-4.
Predicted reactivity: Mouse (96%), Rat (96%), Pig (95%), Chicken (83%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity. Cleaves ASARM peptides between Ser and Glu or Asp residues. Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide. Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides. Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HYP; Metalloendopeptidase homolog PEX; phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets); Phosphate-regulating neutral endopeptidase PHEX; Vitamin D-resistant hypophosphatemic rickets protein; X-linked hypophosphatemia protein
基因别名: HPDR; HPDR1; HYP; HYP1; LXHR; PEX; PHEX; XLH
UniProt ID: (Human) P78562
Entrez Gene ID: (Human) 5251
