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Invitrogen
PHF12 Polyclonal Antibody
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产品信息
PA5-54400
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GGAVNMCYRT LYIGTGADMD VCLTNYGHCN YVSGKHACIF YDENTKHYEL LNYSEHGTTV DNVLYSCDFS EKTPPTPPSS IVAKVQ
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
靶标信息
Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional TLE5 complexes to DNA. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Pf1; PHD factor 1; PHD finger protein 12; PHD zinc finger transcription factor; PHF12; PHF12 (HGNC:20816)
基因别名: KIAA1523; PF1; PHF12
UniProt ID: (Human) Q96QT6
Entrez Gene ID: (Human) 57649
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription corepressor activity
transcription corepressor binding
chromatin binding
protein binding
zinc ion binding
phosphatidylinositol binding
histone binding
chromatin/chromatin-binding, or -regulatory protein
