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Invitrogen
PHF21A Polyclonal Antibody
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PHF21A Antibody (PA5-110104) in WB
Western blot analysis of PHF21A in extracts of various cell lines. Samples were incubated with PHF21A Polyclonal antibody (Product # PA5-110104) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-110104
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 461-680 of human PHF21A (NP_001095272.1).
偶联物
形式
Liquid
浓度
1.11 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TETTFTFPAP VQPVSLPSPT STDGDIHEDF CSVCRKSGQL LMCDTCSRVY HLDCLDPPLK TIPKGMWICP RCQDQMLKKE EAIPWPGTLA IVHSYIAYKA AKEEEKQKLL KWSSDLKQER EQLEQKVKQL SNSISKCMEM KNTILARQKE MHSSLEKVKQ LIRLIHGIDL SKPVDSEATV GAISNGPDCT PPANAATSTP APSPSSQSCT ANCNQGEETK
靶标信息
PHF21A (PHD finger protein 21A) is a component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, PHF21A may act as a scaffold.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BHC80a; BRAF35-HDAC complex protein BHC80; Braf35/HDAC complex (Bhc); BRAF35/HDAC2 complex; BRAF35/HDAC2 complex (80 kDa); mBHC80; PHD finger protein 21A
基因别名: 80kDa; Bhc; BHC80; BM-006; D030065N23Rik; KIAA1696; PFTF1; PHF21A; RGD1560612
UniProt ID: (Human) Q96BD5, (Mouse) Q6ZPK0
Entrez Gene ID: (Human) 51317, (Rat) 362166, (Mouse) 192285
