Search

  • 联系我们
  • 货号直购

Invitrogen

PIAS1/PIAS2 Recombinant Rabbit Monoclonal Antibody (10G6)

查看其他6个PIAS1/PIAS2抗体

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

说明书
证书
实验方案
问题与答案
技术支持
说明书
证书
实验方案
问题与答案
技术支持
说明书
证书
实验方案
问题与答案
技术支持
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

产品信息

MA573419

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:2,000
-

免疫组化（石蜡） (IHC (P))

1:100-1:500
-

免疫组化（冰冻） (IHC (F))

1:100-1:500
-

免疫细胞化学 (ICC/IF)

1:50-1:200
-

流式细胞分析 (Flow)

1:50-1:100
-

免疫沉淀 (IP)

1:20-1:50
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

10G6

抗原

KLH conjugated synthetic peptide derived from human PIAS1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

规格

20 µg

纯化类型

Protein A

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
引用该产品

生物信息学

蛋白别名: Androgen receptor-interacting protein 3; AR interacting protein; ARIP3; DAB2-interacting protein; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; DIP; E3 SUMO-protein ligase PIAS1; E3 SUMO-protein ligase PIAS2; E3 SUMO-protein transferase PIAS1; E3 SUMO-protein transferase PIAS2; GBP; Gu-binding protein; Miz1; Msx-interacting zinc finger protein; Msx-interacting-zinc finger; Msx-interacting-zinc finger protein; nuclear protein that binds to nucleolar RNA helicase Gu protein and to p53; PIAS-NY protein; PIAS1/GBP; PIASxalpha6; PIG23; Protein inhibitor of activated STAT protein 1; Protein inhibitor of activated STAT x; Protein inhibitor of activated STAT2; RING-type E3 ubiquitin transferase PIAS1; RING-type E3 ubiquitin transferase PIAS2; RNA helicase II-binding protein; unnamed protein product; zinc finger, MIZ-type containing 3; zinc finger, MIZ-type containing 4

查看更多 收起

基因别名: 2900068C24Rik; 6330408K17Rik; AI462206; ARIP3; AU018068; DDXBP1; Dib; DIP; GBP; GU/RH-II; MIZ1; PIAS1; PIAS2; PIASX; PIASxalpha; PIASxb; PIASxbeta; SIZ2; ZMIZ3; ZMIZ4

查看更多 收起

UniProt ID: (Human) O75925, (Human) O75928, (Mouse) O88907, (Rat) Q6AZ28, (Mouse) Q8C5D8

查看更多 收起

Entrez Gene ID: (Human) 8554, (Human) 9063, (Mouse) 56469, (Rat) 300772, (Rat) 83422, (Mouse) 17344

查看更多 收起

功能
transcription regulatory region sequence-specific DNA binding DNA binding transcription cofactor activity transcription corepressor activity protein binding zinc ion binding transferase activity SUMO transferase activity enzyme binding protein domain specific binding ubiquitin protein ligase binding metal ion binding SUMO ligase activity DNA-binding transcription factor binding RNA polymerase II sequence-specific DNA binding transcription factor binding protein C-terminus binding transcription factor binding UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ligase activity ribosomal S6-glutamic acid ligase activity coenzyme F420-0 gamma-glutamyl ligase activity coenzyme F420-2 alpha-glutamyl ligase activity protein-glycine ligase activity protein-glycine ligase activity, initiating protein-glycine ligase activity, elongating tubulin-glycine ligase activity protein-glutamic acid ligase activity tubulin-glutamic acid ligase activity estrogen receptor binding glucocorticoid receptor binding androgen receptor binding
参与通路
transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter spermatogenesis metabolic process response to organic substance protein sumoylation androgen receptor signaling pathway response to testosterone negative regulation of sequence-specific DNA binding transcription factor activity regulation of osteoblast differentiation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of dendrite morphogenesis regulation of androgen receptor signaling pathway negative regulation of androgen receptor signaling pathway transforming growth factor beta receptor signaling pathway endoplasmic reticulum unfolded protein response negative regulation of transcription, DNA-templated regulation of macromolecule metabolic process SMAD protein signal transduction G1/S transition of mitotic cell cycle negative regulation of transcription from RNA polymerase II promoter JAK-STAT cascade positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein sumoylation regulation of cell proliferation negative regulation of apoptotic process fat cell differentiation positive regulation of smooth muscle cell differentiation protein-DNA complex assembly negative regulation of nucleic acid-templated transcription double-strand break repair via homologous recombination DNA double-strand break processing cellular response to DNA damage stimulus visual learning positive regulation of protein localization to cell periphery
guarantee_icon

性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

了解更多
help_icon

随时为您服务

获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。

联系技术支持