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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: KFLIKGALVP CSWKLIQSPV TNKKHSESLV PEAERMEPSL CLITALNRK
Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs exhibit various functions, but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in the recognition of either the GPI attachment signal or the lipid portion of GPI. Other PIGs belong to the glycosyltransferase complex and function in the transfer of N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI). A variety of other PIGs play distinct roles in GPI synthesis including mannosylation of the GPI-anchor. PIG-W (Phosphatidylinositol-glycan biosynthesis class W protein) is a 504 amino acid multi-pass membrane protein that functions in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GlcN-PI-acyltransferase; Glucosaminyl-phosphatidylinositol-acyltransferase PIGW; Phosphatidylinositol-glycan biosynthesis class W protein; PIG-W
基因别名: PIGW
Entrez Gene ID: (Human) 284098