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PIK3R4 Polyclonal Antibody
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FIGURE: 1 / 3
PIK3R4 Antibody (600-401-DN7) in ICC/IF
Immunofluorescence Microscopy of Rabbit anti-PIK3R4 antibody. Tissue: human tonsil. Primary antibody: PIK3R4 antibody at 20 µg/mL. Secondary antibody: Fluorescein rabbit secondary antibody at 1:20,000. Localization: PIK3R4 is located on the endosome and membrane. Staining: PIK3R4 as red fluorescent signal.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
600-401-DN7
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-PIK3R4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of human PIK3R4.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150; phosphatidylinositol 3-kinase-associated p150; phosphoinositide 3-kinase adaptor protein; phosphoinositide-3-kinase, regulatory subunit 4, p150; PI3-Kinase p150; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; PI3-kinase VPS15; unnamed protein product
Gene Aliases: 2210010O15Rik; C730038E05Rik; D9Ertd418e; p150; VPS15
UniProt ID: (Human) Q99570, (Rat) P0C0R5, (Mouse) Q8VD65
Entrez Gene ID: (Human) 30849, (Rat) 363131, (Mouse) 75669
pexophagy
protein phosphorylation
protein targeting to lysosome
protein targeting to vacuole
regulation of autophagy
macroautophagy
regulation of macroautophagy
regulation of cytokinesis
receptor catabolic process
phosphatidylinositol-3-phosphate biosynthetic process
cellular response to glucose starvation
protein kinase B signaling
early endosome to late endosome transport
late endosome to vacuole transport
autophagosome maturation
biological_process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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