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Agrisera
PIP (PIP1-1, PIP1-2, PIP1-3, PIP1-4, PIP-5)/aquaporins Polyclonal Antibody, AP
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产品信息
AS09-487-ALP
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated synthetic peptide conserved in Arabidopsis thaliana: PIP1;1, PIP1;2, PIP1;3, PIP1;4, PIP1;5.
偶联物
AP
AP
AP
形式
Liquid
规格
40 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store at 4°C for 12-18 months. A preservative may be added for long time storage up to 2 years.
Specific Species Reactivity: Arabidopsis thaliana, Brassica sp., Jatropha curcas L. cv. Biji Jarak, Mesembryantheum crystallinum, Populus nigra, Populus trichocarpa, Raphanus sativus, Thellungiella salsuginea
靶标信息
PIP1-1, PIP1-2, PIP1-3, PIP1-4, and PIP1-5 encode plant plasma membrane intrinsic protein (PIP1) aquaporins that are targeted predominantly to the plasma membrane, where they contribute to transmembrane movement of water and, for some isoforms, additional small neutral substrates such as CO2. Structurally, PIP1 proteins are typical major intrinsic proteins with six membrane-spanning helices, five connecting loops (including two half-helices bearing the conserved NPA motifs that meet in the membrane to form the pore), and cytosolic N- and C-termini; they assemble as tetramers in the membrane, with each monomer forming an individual channel whose permeability and trafficking can be tuned by post-translational regulation and by hetero-oligomerization with PIP2 aquaporins. Functionally, PIP1 isoforms act as key components of cellular and tissue hydraulic conductivity and can influence organ-level water relations and growth; for example, genetic disruption of PIP1-2 reduces root hydrostatic hydraulic conductivity, consistent with a role in pressure-driven water transport, and PIP1-4 has been implicated in plasma-membrane CO2 and H2O permeability with downstream effects on photosynthetic performance, illustrating that PIP1 channels can couple membrane transport capacity to physiological outputs such as gas exchange, carbon assimilation, and stress-responsive water management.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATHH2; ATPIP1; PIP1; PIP1;1; PIP1;2; PIP1;3; PIP1;4; PIP1;5; PIP1A; PIP1B; PIP1C; PIP1D; PIP1E; plasma membrane intrinsic protein 1; plasma membrane intrinsic protein 1;1; TMP-A; TMP-B; TMP-C; transmembrane protein A; transmembrane protein C
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