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Agrisera
PIP2-1-7/Plasma membrane aquaporin isoforms 1-7 Polyclonal Antibody
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PIP2-1-7/Plasma membrane aquaporin isoforms 1-7 Antibody (AS12-2110) in WB
Representative immunoblot (a) and immunolocalization of PIP 2-1-7 in the Zea mays roots under transmission electron microscope (b). Arrowheads indicate gold particles localized along plasma membrane. Pm - plasma membrane, CW - cell wall. For western-blot (a), 30 µg of the total protein from Zea mays roots was extracted with 0.1 M Tris–HCl (p H 8.0), 2% SDS, 30% sucrose, 5% β-mercaptoetanol and denatured wit... View More
产品信息
AS12-2110
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated synthetic peptide derived from Zea mays PIP2-7 C-terminal.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
保存液
whole serum
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Lactuca sativa, Pisum sativum, Solanum lycopersicum, Zea mays
靶标信息
PIP2-1, PIP2-2, PIP2-3, PIP2-4, PIP2-5, PIP2-6, and PIP2-7 encode members of the plant plasma membrane intrinsic protein (PIP) aquaporin subfamily that predominantly localize to the plasma membrane, where they assemble as tetramers in which each monomer forms an independent channel. Structurally, PIP2 proteins are typical major intrinsic proteins with six transmembrane helices connected by five loops, two conserved NPA motifs in re-entrant loops that meet within the membrane, and an aromatic/arginine selectivity filter that helps define substrate permeability; they often carry regulatory phosphorylation sites in cytosolic terminal regions and can be gated by cellular conditions such as cytosolic acidification. Functionally, PIP2 isoforms act as high-capacity pathways for transmembrane water movement that support tissue hydraulics and rapid water fluxes during development and environmental responses, and specific family members can also facilitate diffusion of small neutral solutes such as hydrogen peroxide, contributing to redox signaling and stress physiology; in several systems, water permeability and gating behavior are further modulated by co-expression and hetero-oligomerization with related PIP aquaporins, enabling dynamic control of membrane transport capacity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AtPIP2;1; PIP2; PIP2;1; PIP2;2; PLASMA MEMBRANE INTRINSIC PROTEIN 2; PLASMA MEMBRANE INTRINSIC PROTEIN 2;1; PLASMA MEMBRANE INTRINSIC PROTEIN 2;2; plasma membrane intrinsic protein 2A; T2N18.7; T2N18_7
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