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Agrisera
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Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
PIP2-1, PIP2-2, and PIP2-3 encode closely related plasma membrane intrinsic protein (PIP) aquaporins that are inserted in the cell surface membrane where they facilitate rapid, regulated transmembrane flux of water and, for some family members, additional small neutral solutes. As major intrinsic protein (MIP) family channels, PIP2 proteins are small (~30 kDa) hydrophobic membrane proteins that typically assemble as tetramers, with each monomer forming an independent pore built from six transmembrane helices connected by five loops; two conserved NPA motifs in opposing half-helices and a narrow aromatic/arginine selectivity region shape the permeation pathway and confer high water selectivity. Functionally, PIP2 isoforms generally show robust water channel activity in heterologous systems and contribute to whole-plant water relations by increasing membrane osmotic water permeability in tissues important for water uptake and transport; PIP2 expression and activity are also modulated during development and environmental stress, consistent with roles in adjusting cellular and tissue hydraulics during changing water availability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: At2g37180; AtPIP2;1; PIP2; PIP2;1; PIP2;2; PIP2;3; PIP2A; PIP2B; PIP2C; PLASMA MEMBRANE INTRINSIC PROTEIN 2; PLASMA MEMBRANE INTRINSIC PROTEIN 2;1; PLASMA MEMBRANE INTRINSIC PROTEIN 2;2; RD28; T2N18.6; T2N18.7; T2N18_7