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Invitrogen
PITPNM1 Polyclonal Antibody
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PITPNM1 Antibody (PA5-18266) in ICC/IF
Immunocytochemical analysis of PITPNM1 in A549 cells using a PITPNM1 polyclonal antibody (Product #PA5-18266). A549 cells were permeabilized with 0.15% Triton. Cells were incubated with 10 µg/mL of primary antibody for one hour followed by an Alexa Fluor 488 secondary antibody at a concentration of 2 µg/mL. Cytoplasmic and endoplasmic staining can be seen as shown above. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by an Alexa Fluor 488 secondary antibody (2 µg/mL).
产品信息
PA5-18266
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (KARSISLKLDSEE) corresponding to the C-terminus amino acids of PITPNM1 (aa 1232-1244).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine, canine and human based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
靶标信息
Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Drosophila retinal degeneration B homolog; FLJ44997; Membrane-associated phosphatidylinositol transfer protein 1; NIR-2; phosphatidylinositol transfer protein, membrane associated 1; Phosphatidylinositol transfer protein, membrane-associated 1; PITPnm 1; PYK2 N-terminal domain-interacting receptor 2; retinal degeneration B alpha 1
基因别名: DRES9; NIR2; PITPNM; PITPNM1; Rd9; RDGB; RDGB1; RDGBA; RDGBA1
UniProt ID: (Human) O00562
Entrez Gene ID: (Human) 9600
