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PITRM1 Monoclonal Antibody (1H3)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00010531-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1H3
抗原
PITRM1 (AAH01150, 1 a.a. approximately 534 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MRPDDKYHEK QAQVEATKLK QKVEALSPGD RQQIYEKGLE LRSQQSKPQD ASCLPALKVS DIEPTIPVTE LDVVLTAGDI PVQYCAQPTN GMVYFRAFSS LNTLPEELRP YVPLFCSVLT KLGCGLLDYR EQAQQIELKT GGMSASPHVL PDDSHMDTYE QGVLFSSLCL DRNLPDMMQL WSEIFNNPCF EEEEHFKVLV KMTAQELANG IPDSGHLYAS IRAGRTLTPA GDLQETFSGM DQVRLMKRIA EMTDIKPILR KLPRIKKHLL NGDNMRCSVN ATPQQMPQTE KAVEDFLRSI GRSKKERRPV RPHTVEKPVP SSSGGDAHVP HGSQVIRKLV MEPTFKPWQM KTHFLMPFPV NYVGECIRTV PYTDPDHASL KILARLMTAK FLHTEIREKG GAYGGGAKLS HNGIFTLYSY RDPNTIETLQ SFGKAVDWAK SGKFTQQDID EAKLSVFSTV DAPVAPSDKG MDHFLYGLSD EMKQAHREQL FAVSHDKLLA VSDRYLGTGK STHGLAILGP ENPKIAKDPS WIIR
靶标信息
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hPreP; Metalloprotease 1; Pitrilysin metalloproteinase 1; Presequence protease, mitochondrial
基因别名: KIAA1104; MP1; PITRM1; PREP
Entrez Gene ID: (Human) 10531
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
