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Invitrogen
PJA2 Polyclonal Antibody
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产品信息
PA5-69216
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of human PJA2 (aa 24-73)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
靶标信息
Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA-mediated long-term memory processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase Praja2; neurodegeneration associated protein 1; praja 2, RING-H2 motif containing; praja-2; praja2; protein carrying the RING-H2 sequence motif; RING finger protein 131; RING-H2 finger ubiquitin ligase; neurodap1; RING-type E3 ubiquitin transferase Praja-2; unnamed protein product
基因别名: mKIAA0438; Neurodap1
UniProt ID: (Mouse) Q80U04
Entrez Gene ID: (Mouse) 224938
inflammatory response
long-term memory
protein ubiquitination
positive regulation of toll-like receptor 2 signaling pathway
regulation of macrophage activation
proteasome-mediated ubiquitin-dependent protein catabolic process
innate immune response
positive regulation of JNK cascade
positive regulation of cAMP/PKA signal transduction
positive regulation of p38MAPK cascade
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