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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive test controls include: HeLa, Jurkat, 293T, Mouse brain, Rat brain.
Immunogen sequence: MTKHPAKRLG CGPEGERDVR EHAFFRRIDW EKLENREIQP PFKPKVCGKG AENFDKFFTR GQPVLTPPDQ LVIANIDQSD FEGFSYVNPQ FVHPILQSAV
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms ( alpha, betaI, betaII and gamma) and novel (n) PKC isoforms ( delta, epsilon, zeta, eta and theta). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and epsilon are independent of Ca2+.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AAG6; aging-associated gene 6; alternatively spliced; aPKC-lambda/iota; atypical protein kinase C; atypical protein kinase C-lambda/iota; nPKC-delta; nPKC-epsilon; nPKC-eta; nPKC-iota; nPKC-theta; nPKC-zeta; PCK epsilon; PKC epsilon; PKC gamma; PKC lambda; PKC theta; PKC zeta; PKC-A; PKC-alpha; PKC-B; PKC-beta; PKC-gamma; PKC-L; PKCdelta; PKCdeltaVIII; PRKC-lambda/iota; Prkce; diacylglycerol sensitive, calcium insensitive ser/thr kinase; protein kinase; protein kinase C alpha-polypeptide; protein kinase C beta I; protein kinase C beta II; protein kinase C beta-1; protein kinase C beta-II; protein kinase C delta subspecies; protein kinase C delta VIII; protein kinase C epsilon subspecies; protein kinase C type I (gamma type); protein kinase C type II; protein kinase C type III; protein kinase C zeta subspecies; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide; protein kinase C, delta IV; protein kinase C, delta V; protein kinase C, lambda; protein kinase C, zeta subspecies; protein kinase c-alpha; protein kinase C[d]; Protein uPEP2; tyrosine-protein kinase PRKCD; unnamed protein product
基因别名: 14-3-3-zetaisoform; 2310021H13Rik; 5830406C15Rik; A130035A12Rik; AAG6; ALPS3; aPKClambda; aPKCzeta; CVID9; D14Ertd420e; DXS1179E; MAY1; mKIAA4165; nPKC-delta; nPKC-epsilon; nPKC-eta; nPKC-iota; nPKC-theta; nPKC-zeta; PKC; PKC-0; PKC-alpha; PKC-B; PKC-Beta; PKC-gamma; PKC-L; PKC-theta; PKC-ZETA; PKC2; PKC[d]; PKC[e]; PKCA; PKCalpha; PKCB; PKCbeta; PKCC; PKCD; PKCdelta; PKCE; PKCepsilon; PKCG; PKCgamma; Pkch; PKCI; PKCI(2); PKCI(3); PKCI+/-; PKCL; PKClambda; Pkcq; PKCtheta; Pkcz; Prkc; PRKCB1; PRKCB2; Prkcc; PRKCL; PRKCT; r14-3-3; RATPKCI; SCA14; uORF2; zetaPKC
UniProt ID: (Human) P17252, (Human) P05771, (Human) Q05655, (Human) Q02156, (Human) P05129, (Human) P24723, (Human) P41743, (Human) Q04759, (Human) Q05513, (Mouse) P20444, (Rat) P05696, (Rat) P68403, (Mouse) P68404, (Mouse) P28867, (Rat) P09215, (Rat) P09216, (Mouse) P16054, (Rat) P63319, (Mouse) P63318, (Rat) Q64617, (Mouse) P23298, (Mouse) Q62074, (Rat) F1M7Y5, (Mouse) Q02111, (Mouse) Q02956, (Rat) P09217
Entrez Gene ID: (Human) 5578, (Human) 5579, (Human) 5580, (Human) 5581, (Human) 5582, (Human) 5583, (Human) 5584, (Human) 5588, (Human) 5590, (Mouse) 18750, (Rat) 24680, (Rat) 25023, (Mouse) 18751, (Mouse) 18753, (Rat) 170538, (Rat) 29340, (Mouse) 18754, (Rat) 24681, (Mouse) 18752, (Rat) 81749, (Mouse) 18755, (Mouse) 18759, (Rat) 84006, (Rat) 85420, (Mouse) 18761, (Mouse) 18762, (Rat) 25522