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Invitrogen

PKC delta/theta Recombinant Rabbit Monoclonal Antibody (15C18)

查看其他4个PKC delta/theta抗体

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产品信息

MA573430

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:1,000-1:5,000
-

免疫组化（石蜡） (IHC (P))

1:100-1:500
-

免疫组化（冰冻） (IHC (F))

1:100-1:500
-

免疫细胞化学 (ICC/IF)

1:100-1:500
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

15C18

抗原

KLH conjugated synthetic peptide derived from human PKC delta.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.5 mg/mL

规格

150 µg

纯化类型

Protein A

保存液

TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.02% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

PRKCD (Protein Kinase C Delta) is a Protein Coding gene. Diseases associated with PRKCD includeAutoimmune Lymphoproliferative Syndrome, Type IiiandSystemic Lupus Erythematosus 16. Among its related pathways areRole of Calcineurin dependent NFAT signaling in lymphocytesandWnt Signaling Pathway and Pluripotency. Gene Ontology (GO) annotations related to this gene includetransferase activity, transferring phosphorus containing groupsandprotein tyrosine kinase activity. An important paralog of this gene isPRKCQ (PKC theta).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: nPKC-delta; nPKC-theta; PKC theta; Protein kinase C delta type; protein kinase C delta variant IX; Protein kinase C theta type; protein kinase C, delta IV; protein kinase C, delta V; protein kinase C[d]; SDK-1; Tyrosine-protein kinase PRKCD

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基因别名: A130035A12Rik; AI385711; AW494342; D14Ertd420e; PKC-0; PKC-theta; PKC[d]; PKCD; PKCdelta; Pkcq; PKCtheta; PRKCD; PRKCQ; PRKCT

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UniProt ID: (Mouse) P28867, (Rat) P09215, (Mouse) Q02111

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Entrez Gene ID: (Mouse) 18753, (Rat) 170538, (Mouse) 18761, (Rat) 85420

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功能
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein kinase C activity calcium-independent protein kinase C activity non-membrane spanning protein tyrosine kinase activity ATP binding enzyme activator activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups enzyme binding protein kinase binding insulin receptor substrate binding metal ion binding TIR domain binding protein binding non-receptor serine/threonine protein kinase
参与通路
protein phosphorylation apoptotic process response to oxidative stress cell cycle aspartate transport immunoglobulin mediated immune response phosphorylation peptidyl-threonine phosphorylation termination of signal transduction negative regulation of actin filament polymerization interleukin-10 production interleukin-12 production positive regulation of superoxide anion generation regulation of actin cytoskeleton organization collagen metabolic process negative regulation of glial cell apoptotic process cellular response to oxidative stress positive regulation of protein dephosphorylation intracellular signal transduction B cell proliferation neutrophil activation regulation of phosphorylation defense response to bacterium positive regulation of apoptotic process positive regulation of MAP kinase activity negative regulation of MAP kinase activity positive regulation of MAPK cascade positive regulation of glucose import negative regulation of insulin receptor signaling pathway protein autophosphorylation negative regulation of peptidyl-tyrosine phosphorylation negative regulation of filopodium assembly negative regulation of platelet aggregation cellular senescence positive regulation of phospholipid scramblase activity positive regulation of ceramide biosynthetic process positive regulation of glucosylceramide catabolic process positive regulation of sphingomyelin catabolic process positive regulation of response to DNA damage stimulus positive regulation of apoptotic signaling pathway response to hypoxia aging response to heat response to mechanical stimulus response to glucose response to organonitrogen compound response to organic cyclic compound cellular response to insulin stimulus cellular response to glucose starvation response to drug response to hydrogen peroxide positive regulation of catalytic activity response to amino acid response to ethanol immune system process regulation of transcription, DNA-templated membrane protein ectodomain proteolysis inflammatory response regulation of G2/M transition of mitotic cell cycle positive regulation of interleukin-17 production positive regulation of interleukin-4 production positive regulation of T cell proliferation positive regulation of NF-kappaB import into nucleus positive regulation of interleukin-2 biosynthetic process positive regulation of protein secretion positive regulation of T cell activation positive regulation of NF-kappaB transcription factor activity positive regulation of filopodium assembly positive regulation of stress fiber assembly negative regulation of T cell apoptotic process regulation of platelet aggregation positive regulation of T-helper 17 type immune response positive regulation of T-helper 2 cell activation regulation of vasoconstriction neuron differentiation response to insulin tissue regeneration respiratory burst
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