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Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: PVHSTMPGTV TSSCSPGNNS RPSSPGSGLH ASSPTASQNN SKAAVNSASS FNSSGSWYRW NHSTYL
Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 90%.
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 11-Oct; FLJ40063; MGC126698; Oct-11; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF-11; POU domain transcription factor OCT11a; POU domain, class 2, transcription factor 3; Transcription factor PLA-1; Transcription factor Skn-1
Gene Aliases: Epoc-1; OCT-11; OCT11; OTF-11; OTF11; PLA-1; PLA1; POU2F3; Skn-1a
UniProt ID: (Human) Q9UKI9
Entrez Gene ID: (Human) 25833
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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