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Abnova
PLA2G1B Monoclonal Antibody (1B3)
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产品信息
H00005319-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1B3
抗原
PLA2G1B (AAH05386, 17 a.a. approximately 70 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: SGISPRAVWQ FRKMIKCVIP GSDPFLEYNN YGCYCGLGGS GTPVDELDKQ KQRV
靶标信息
Phospholipase A2 catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Group IB phospholipase A2; MGC119834; MGC119835; Phosphatidylcholine 2-acylhydrolase 1B; Phospholipase A2; phospholipase A2, group IB (pancreas)
基因别名: PLA2; PLA2A; PLA2G1B; PPLA2
UniProt ID: (Human) P04054
Entrez Gene ID: (Human) 5319
activation of MAPK activity
innate immune response in mucosa
neutrophil mediated immunity
fatty acid biosynthetic process
phosphatidic acid biosynthetic process
actin filament organization
signal transduction
positive regulation of calcium ion transport into cytosol
glucose transport
leukotriene biosynthetic process
antibacterial humoral response
neutrophil chemotaxis
activation of phospholipase A2 activity
interleukin-8 production
cellular response to insulin stimulus
intracellular signal transduction
phosphatidylglycerol acyl-chain remodeling
phosphatidylinositol acyl-chain remodeling
phosphatidylserine acyl-chain remodeling
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
multicellular organism lipid catabolic process
positive regulation of DNA replication
positive regulation of transcription from RNA polymerase II promoter
phosphatidylcholine metabolic process
positive regulation of fibroblast proliferation
arachidonic acid secretion
positive regulation of protein secretion
positive regulation of immune response
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
