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Abnova
PLA2G2F Polyclonal Antibody, MaxPab™
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PLA2G2F Antibody (H00064600-B01P) in WB
Western Blot analysis of PLA2G2F expression in transfected 293T cell line (H00064600-T01) by PLA2G2F MaxPab polyclonal antibody.
Lane 1: PLA2G2F transfected lysate(23.21 KDa).
Lane 2: Non-transfected lysate.
Lane 1: PLA2G2F transfected lysate(23.21 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00064600-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PLA2G2F (NP_073730.3, 1 a.a. approximately 211 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MADGAKANPK GFKKKVLDRC FSGWRGPRFG ASCPSRTSRS SLGMKKFFTV AILAGSVLST AHGSLLNLKA MVEAVTGRSA ILSFVGYGCY CGLGGRGQPK DEVDWCCHAH DCCYQELFDQ GCHPYVDHYD HTIENNTEIV CSDLNKTECD KQTCMCDKNM VLCLMNQTYR EEYRGFLNVY CQGPTPNCSI YEPPPEEVTC SHQSPAPPAP P
靶标信息
May play a role in lipid mediator production in inflammatory conditions, by providing arachidonic acid to downstream cyclooxygenases and lipoxygenases. Phospholipase A2, which catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:11112443). Hydrolyzes phosphatidylethanolamine more efficiently than phosphatidylcholine, with only a modest preference for arachidonic acid versus linoelic acid at the sn-2 position. Comparable activity toward 1-palmitoyl-2-oleoyl-phosphatidylserine vesicles to that toward 1-palmitoyl-2-oleoyl-phosphatidylglycerol. Hydrolyzes phosphatidylglycerol versus phosphatidylcholine with a 15-fold preference (PubMed:11112443). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GIIF sPLA2; Group IIF secretory phospholipase A2; Phosphatidylcholine 2-acylhydrolase 2F; phospholipase A2, group IIF; sPLA2-IIF
基因别名: PLA2G2F
UniProt ID: (Human) Q9BZM2
Entrez Gene ID: (Human) 64600
phosphatidic acid biosynthetic process
biological_process
lipid catabolic process
phosphatidylglycerol acyl-chain remodeling
phosphatidylinositol acyl-chain remodeling
phosphatidylserine acyl-chain remodeling
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
negative regulation of T cell proliferation
