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Abnova
PLA2G6 Polyclonal Antibody, MaxPab™
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产品信息
H00008398-D01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PLA2G6 (NP_001004426.1, 1 a.a. approximately 752 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MQFFGRLVNT FSGVTNLFSN PFRVKEVAVA DYTSSDRVRE EGQLILFQNT PNRTWDCVLV NPRNSQSGFR LFQLELEADA LVNFHQYSSQ LLPFYESSPQ VLHTEVLQHL TDLIRNHPSW SVAHLAVELG IRECFHHSRI ISCANCAENE EGCTPLHLAC RKGDGEILVE LVQYCHTQMD VTDYKGETVF HYAVQGDNSQ VLQLLGRNAV AGLNQVNNQG LTPLHLACQL GKQEMVRVLL LCNARCNIMG PNGYPIHSAM KFSQKGCAEM IISMDSSQIH SKDPRYGASP LHWAKNAEMA RMLLKRGCNV NSTSSAGNTA LHVAVMRNRF DCAIVLLTHG ANADARGEHG NTPLHLAMSK DNVEMIKALI VFGAEVDTPN DFGETPTFLA SKIGRQLQDL MHISRARKPA FILGSMRDEK RTHDHLLCLD GGGVKGLIII QLLIAIEKAS GVATKDLFDW VAGTSTGGIL ALAILHSKSM AYMRGMYFRM KDEVFRGSRP YESGPLEEFL KREFGEHTKM TDVRKPKVML TGTLSDRQPA ELHLFRNYDA PETVREPRFN QNVNLRPPAQ PSDQLVWRAA RSSGAAPTYF RPNGRFLDGG LLANNPTLDA MTEIHEYNQD LIRKGQANKV KKLSIVVSLG TGRSPQVPVT CVDVFRPSNP WELAKTVFGA KELGKMVVDC CTDPDGRAVD RARAWCEMVG IQYFRLNPQL GTDIMLDEVS DTVLVNALWE TEVYIYEHRE EFQKLIQLLL SP
靶标信息
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only two of them have been determined to date.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2-lysophosphatidylcholine acylhydrolase; 85 kDa calcium-independent phospholipase A2; 85/88 kDa calcium-independent phospholipase A2; CaI-PLA2; Group VI phospholipase A2; GVI PLA2; Intracellular membrane-associated calcium-independent phospholipase A2 beta; iPLA2-beta; neurodegeneration with brain iron accumulation 2; Palmitoyl-CoA hydrolase; Patatin-like phospholipase domain-containing protein 9; phospholipase A2, group VI (cytosolic, calcium-independent); PNPLA9
基因别名: BB112799; CaI-PLA2; GVI; INAD1; iPLA(2)beta; iPLA2; IPLA2-VIA; iPLA2beta; NBIA2; NBIA2A; NBIA2B; PARK14; PLA2; PLA2G6; PLPLA9; PNPLA9
UniProt ID: (Human) O60733, (Mouse) P97819
Entrez Gene ID: (Human) 8398, (Mouse) 53357
positive regulation of protein phosphorylation
chemotaxis
positive regulation of cytosolic calcium ion concentration
memory
urinary bladder smooth muscle contraction
lipid catabolic process
antibacterial humoral response
cardiolipin biosynthetic process
response to endoplasmic reticulum stress
positive regulation of insulin secretion involved in cellular response to glucose stimulus
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of vasodilation
positive regulation of exocytosis
negative regulation of synaptic transmission, glutamatergic
maternal process involved in female pregnancy
positive regulation of protein kinase C signaling
positive regulation of release of cytochrome c from mitochondria
positive regulation of arachidonic acid secretion
regulation of store-operated calcium channel activity
positive regulation of ceramide biosynthetic process
lipid metabolic process
metabolic process
