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Invitrogen
PLAC1 Humanized Recombinant Human Monoclonal Antibody (SAA2100)
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产品信息
MA5-54658
产品规格
种属反应
Human
宿主/亚型
Human
/ VHH-hFc
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SAA2100
抗原
Recombinant Human PLAC1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Compatible with Direct ELISA
靶标信息
PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cancer/testis antigen 92; PLAC1; placenta-specific 1; Placenta-specific protein 1
基因别名: CT92; OOSP2L; PLAC1
UniProt ID: (Human) Q9HBJ0
Entrez Gene ID: (Human) 10761
