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Invitrogen
PLCB1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-111460
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EEEVKKEADP GETPSEAPSE ARTTPAENGV NHTTTLTPKP PSQALHSQPA PGSVKAPAKT EDLIQSVLTE VEAQTIEELK QQKSFVK
Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 93%.
靶标信息
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide-specific phospholipase c; phospholipase C, beta 1 (phosphoinositide-specific); phospholipase C-I; triphosphoinositide phosphodiesterase; unnamed protein product
基因别名: DEE12; EIEE12; PI-PLC; PLC-154; PLC-beta-1; PLC-I; PLC154; PLCB1A; PLCB1B
UniProt ID: (Human) Q9NQ66
Entrez Gene ID: (Human) 23236
phosphatidylinositol phospholipase C activity
phospholipase C activity
GTPase activator activity
calcium ion binding
protein binding
calmodulin binding
lamin binding
phosphatidylinositol-4,5-bisphosphate binding
phosphoric diester hydrolase activity
enzyme binding
identical protein binding
phosphatidylinositol phospholipase C activity
G2/M transition of mitotic cell cycle
lipid metabolic process
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
G-protein coupled acetylcholine receptor signaling pathway
glutamate receptor signaling pathway
learning
memory
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of glycoprotein biosynthetic process
lipid catabolic process
cerebral cortex development
phosphatidylinositol catabolic process
positive regulation of interleukin-12 production
inositol trisphosphate metabolic process
response to monosaccharide
intracellular signal transduction
interleukin-12-mediated signaling pathway
interleukin-15-mediated signaling pathway
positive regulation of embryonic development
response to peptide hormone
fat cell differentiation
positive regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of JNK cascade
phosphatidylinositol metabolic process
insulin-like growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of developmental growth
release of sequestered calcium ion into cytosol
activation of meiosis involved in egg activation
interleukin-1-mediated signaling pathway
regulation of fertilization
postsynaptic modulation of chemical synaptic transmission
regulation of retrograde trans-synaptic signaling by endocanabinoid
positive regulation of G1/S transition of mitotic cell cycle
cellular response to fluoride
regulation of establishment of endothelial barrier
cellular response to vasopressin
cellular response to ionomycin
cellular response to glyceraldehyde
positive regulation of acrosome reaction
negative regulation of monocyte extravasation
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