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Immunogen sequence: KSFVKLQKKH YKEMKDLVKR HHKKTTDLIK EHTTKYNEIQ NDYLRRRAAL EKSAKKDSKK KSEPSSPDHG SSTIEQDLAA LDAEMTQKLI DLKDKQQQQL LNLRQEQYYS EKYQKREHIK LLIQKLTDVA EECQNNQLKK LKEICEKEKK ELKKKMDKKR QEKITEAKSK DKSQMEEEKT EMIRSYIQEV VQYIKRLEEA QSKRQEKLVE KHKEIRQQIL DEKPKLQVEL EQEYQDKFKR LPLEILEFVQ EAMKGKISED SNHGSAPLSL SSDPGKVNHK TPSSEELGGD IPGKEFDTPL; Positive Samples: NCI-H460; Cellular Location: Cytoplasm, Nucleus membrane
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; phosphoinositidase C; phosphoinositide phospholipase C; Phosphoinositide phospholipase C-beta-1; phosphoinositide-specific phospholipase c; phospholipase C, beta 1 (phosphoinositide-specific); Phospholipase C-beta-1; phospholipase C-beta-1a; Phospholipase C-beta1; Phospholipase C-I; PLC-154; PLC-beta-1; PLC-I; triphosphoinositide phosphodiesterase
基因别名: 3110043I21Rik; AI132408; EIEE12; KIAA0581; mKIAA0581; Phosphb; PI-PLC; PLC'1; PLC-154; PLC-beta-1; PLC-I; PLC154; Plcb; PLCB1; PLCB1A; PLCB1B; PLCbeta1; RATPHOSPHB
UniProt ID: (Human) Q9NQ66, (Rat) P10687, (Mouse) Q9Z1B3
Entrez Gene ID: (Human) 23236, (Rat) 24654, (Mouse) 18795