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Invitrogen
PLCB3 Polyclonal Antibody
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PLCB3 Antibody (PA5-120077) in IHC (P)
Immunohistochemistry analysis of PLCB3 in paraffin-embedded rat brain. Samples were incubated with PLCB3 Polyclonal antibody (Product # PA5-120077) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-120077
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1010-1234 of human PLC beta 3 (PLCB3) (NP_001303243.1).
偶联物
形式
Liquid
浓度
1.65 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: OVCAR8, Mouse lung, Rat lung. The target is usually found in the following locations: Membrane, Peripheral membrane protein.
Immunogen sequence: GALGGAADVE DTKEGEDEAK RYQEFQNRQV QSLLELREAQ VDAEAQRRLE HLRQALQRLR EVVLDANTTQ FKRLKEMNER EKKELQKILD RKRHNSISEA KMRDKHKKEA ELTEINRRHI TESVNSIRRL EEAQKQRHDR LVAGQQQVLQ QLAEEEPKLL AQLAQECQEQ RARLPQEIRR SLLGEMPEGL GDGPLVACAS NGHAPGSSGH LSGADSESQE ENTQL
靶标信息
PLCB3 encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; phosphoinositide-specific phospholipase c; phospholipase C beta 3; phospholipase C, beta 3 (phosphatidylinositol-specific); Phospholipase C-beta-3; PLC beta 3; PLC-beta-3; PLC-beta3; PLCbeta3
基因别名: mKIAA4098; PLCB3
UniProt ID: (Human) Q01970, (Mouse) P51432
Entrez Gene ID: (Human) 5331, (Rat) 29322, (Mouse) 18797
regulation of systemic arterial blood pressure
post-Golgi vesicle-mediated transport
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
chemical synaptic transmission
lipid catabolic process
intracellular signal transduction
inositol phosphate metabolic process
cell-cell adhesion
phospholipid catabolic process
lipid metabolic process
signal transduction
