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Invitrogen
PLEKHJ1 Polyclonal Antibody
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产品信息
PA5-21897
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GNRPX. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HeLa, Jurkat, NT2D1, mouse liver.
Predicted reactivity: Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The PLEKHJ1 (Pleckstrin Homology Domain Containing, Family J Member 1) gene encodes a protein that is involved in signal transduction and cytoskeletal organization. Located on chromosome 11, the PLEKHJ1 protein contains a pleckstrin homology (PH) domain, which facilitates its binding to phosphoinositides and the subsequent interaction with cellular membranes. This interaction is vital for various cellular processes, including the regulation of cell shape, motility, and intracellular trafficking. The precise biological functions of PLEKHJ1 are still being elucidated, but its role in these signaling pathways underscores its importance in maintaining cellular architecture and function. Alterations in PLEKHJ1 expression or mutations can have significant implications for cellular dynamics and have been linked to certain pathological conditions, including cancer.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: guanine nucleotide releasing protein x; Guanine nucleotide-releasing protein x; PH domain-containing family J member 1; pleckstrin homology domain containing, family J member 1; Pleckstrin homology domain-containing family J member 1
基因别名: 9530063M10Rik; GNRPX; PLEKHJ1
UniProt ID: (Human) Q9NW61, (Mouse) Q9D240
Entrez Gene ID: (Human) 55111, (Mouse) 78670
