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Invitrogen
PLM Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-79288
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human FXYD1 recombinant protein (Position: E21-R92).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Liver Tissue, Rat Cardiac Muscle Tissue, Mouse Cardiac Muscle Tissue, HEPG2 whole cell, HELA whole cell. IHC: mouse cardiac muscle tissue, rat cardiac muscle tissue, human prostatic cancer tissue.
Target Information
This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: phospholemman transcript variant b; sarcolemmal membrane protein; Sodium Potassium ATPase; sodium/potassium-transporting ATPase subunit FXYD1; unnamed protein product
Gene Aliases: 0610012C17Rik; 1110006M24Rik; PLM; Pml
UniProt ID: (Human) O00168, (Rat) O08589, (Mouse) Q9Z239
Entrez Gene ID: (Human) 5348, (Rat) 58971, (Mouse) 56188
ion transport
anion transport
negative regulation of protein glutathionylation
organic acid transport
regulation of ion transport
regulation of cytosolic calcium ion concentration
regulation of cardiac muscle cell contraction
regulation of cardiac muscle cell membrane potential
regulation of sodium ion transmembrane transport
positive regulation of sodium ion export from cell
regulation of sodium:potassium-exchanging ATPase activity
positive regulation of organic acid transport
chloride transport
cellular sodium ion homeostasis
muscle contraction
regulation of heart contraction
establishment or maintenance of transmembrane electrochemical gradient
cellular potassium ion homeostasis
sodium ion export from cell
chloride transmembrane transport
hydrogen ion transmembrane transport
potassium ion import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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