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Invitrogen
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Antibody detects endogenous levels of total PLSCR2.
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.; FUNCTION: Isoform 1 has no prospholipid scramblase activity, due to the lack of a N-terminal proline-rich domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ca(2+)-dependent phospholipid scramblase 2; Phospholipid scramblase 2; PL scramblase 2
基因别名: PLSCR2
UniProt ID: (Human) Q9NRY7, (Mouse) Q9DCW2
Entrez Gene ID: (Human) 57047, (Mouse) 18828