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Invitrogen
PLSCR3 Polyclonal Antibody
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产品信息
PA5-27590
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human PLSCR3. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.77 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: H1299, mouse stomach.
Predicted reactivity: Mouse (94%), Rat (94%), Rhesus Monkey (99%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ca 2+ dependent phospholipid scramblase 3; Ca(2+)-dependent phospholipid scramblase 3; Phospholipid scramblase 3; PL scramblase 3
基因别名: 2210403O21Rik; 2610037N06Rik; ESTM3; PLSCR3; X83310
UniProt ID: (Human) Q9NRY6, (Mouse) Q9JIZ9
Entrez Gene ID: (Human) 57048, (Mouse) 70310
