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Invitrogen
PLSCR3 Polyclonal Antibody
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产品信息
PA5-64376
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PFLPKFSIQD ADRQTVLRVV GPCWTCGCGT DTNFEVKTRD ESRSVGRISK QWGGLVREAL TDADDFG
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 91%.
靶标信息
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ca(2+)-dependent phospholipid scramblase 3; Phospholipid scramblase 3; PL scramblase 3
基因别名: PLSCR3
UniProt ID: (Human) Q9NRY6
Entrez Gene ID: (Human) 57048
