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Invitrogen
PLXNA4 Polyclonal Antibody
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图: 1 / 4
PLXNA4 Antibody (PA5-115772) in ICC/IF
Immunocytochemistry analysis of PLXNA4 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115772) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115772
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PLXNA4(Accession Q9HCM2), corresponding to amino acid residues A1849-S1894.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Plexin A4.
靶标信息
PLXNA4 is a protein coding gene. Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OTTHUMP00000207245; Plexin-A4
基因别名: 9330117B14; KIAA1550; mKIAA1550; Plxa4; PLXNA4; PLXNA4A; PLXNA4B; UNQ2820/PRO34003
UniProt ID: (Mouse) Q80UG2
Entrez Gene ID: (Mouse) 243743, (Rat) 312213
nervous system development
axon guidance
cranial nerve morphogenesis
facial nerve morphogenesis
facial nerve structural organization
glossopharyngeal nerve morphogenesis
trigeminal nerve morphogenesis
trigeminal nerve structural organization
vagus nerve morphogenesis
postganglionic parasympathetic fiber development
chemorepulsion of branchiomotor axon
anterior commissure morphogenesis
sympathetic nervous system development
neuron projection morphogenesis
regulation of axon extension involved in axon guidance
regulation of negative chemotaxis
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in axon guidance
signal transduction
motor neuron axon guidance
branchiomotor neuron axon guidance
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