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Invitrogen
PLXNB1 Polyclonal Antibody
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图: 1 / 2
PLXNB1 Antibody (PA5-143747) in ICC/IF
Immunocytochemistry analysis of PLXNB1 in rat PC12 cells differentiated with NGF. The cells were probed with rabbit PLXNB1 polyclonal antibody (Product # PA5-143747) and mouse CD100 (SEMA4D) monoclonal antibody (Product # MA5-47680), then the antibodies were detected using appropriate secondary antibody conjugated to DyLight® 594.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-143747
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region of human Plexin B1. This sequence has high homology with similar regions in rat and mouse Plexin B1, and has low homology to other plexin family members.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.0 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 1mg/mL BSA, 50% glycerol
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects 300, 150, and 100 kDa* bands on SDS-PAGE immunoblots of mouse liver and rat PC12 cells. These bands correspond to the full length and proteolytically processed forms of Plexin B1. In mouse liver, this antibody detects 300 and 100 kDa forms of Plexin B1.
靶标信息
Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1gene. Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: plexin 1; plexin-A1; Plexin-B1; Semaphorin receptor SEP
基因别名: 2900002G15Rik; AU042020; KIAA0407; mKIAA0407; PLXN5; PLXNB1; SEP
UniProt ID: (Mouse) Q8CJH3
Entrez Gene ID: (Rat) 316009, (Mouse) 235611
negative regulation of cell adhesion
regulation of cell shape
positive regulation of phosphatidylinositol 3-kinase signaling
negative regulation of osteoblast proliferation
ossification involved in bone maturation
neuron projection morphogenesis
positive regulation of axonogenesis
regulation of cytoskeleton organization
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
signal transduction
positive regulation of GTPase activity
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