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Invitrogen
PMCH Polyclonal Antibody
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PMCH Antibody (PA5-84521) in IHC (P)
Immunohistochemistry analysis of PMCH in human cerebral cortex, hypothalamus, liver and testis. Samples were incubated with PMCH polyclonal antibody (Product # PA5-84521). Shows similar protein distribution across tissues to independent PMCH antibody (Product # PA5-83802) (B).
产品信息
PA5-84521
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KGSVAFPAEN GVQNTESTQE KREIGDEENS AKFPIGRRDF DMLRCMLGRV YRPCW
Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 98%.
靶标信息
MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: neuropeptide-glutamic acid-isoleucine (NEI); neuropeptide-glycine-glutamic acid (NGE); prepro-MCH; prepro-melanin-concentrating hormone; Pro-MCH; pro-melanin-concentrating hormone
基因别名: A230109K23Rik; MCH; PMCH; ppMCH
UniProt ID: (Human) P20382, (Mouse) P56942
Entrez Gene ID: (Human) 5367, (Mouse) 110312
neuropeptide signaling pathway
chemical synaptic transmission
multicellular organism development
spermatogenesis
feeding behavior
cell differentiation
regulation of heart rate
positive regulation of cytosolic calcium ion concentration
response to cold
negative regulation of synaptic transmission, dopaminergic
glucose homeostasis
drinking behavior
negative regulation of blood pressure
positive regulation of circadian sleep/wake cycle, REM sleep
regulation of neuronal synaptic plasticity
