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Invitrogen
PMEPA1 Polyclonal Antibody
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产品信息
PA5-101231
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PMEPA1(Accession Q969W9), corresponding to amino acid residues F72-P122.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total PMEPA1.
靶标信息
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Nedd4 WW binding protein 4; NEDD4 WW domain-binding protein 4; Prostate transmembrane protein androgen induced 1; Protein TMEPAI; Solid tumor-associated 1 protein; solid tumor-associated gene 1; Transmembrane prostate androgen-induced protein; transmembrane, prostate androgen induced RNA; type 1b transmembrane protein; unknown function; unnamed protein product
基因别名: 2210418I02Rik; AW455466; Erg1.2; N4wbp4; PMEPA1; STAG1; TMEPAI
UniProt ID: (Human) Q969W9
Entrez Gene ID: (Human) 56937, (Mouse) 65112
negative regulation of signal transduction
negative regulation of transforming growth factor beta receptor signaling pathway
androgen receptor signaling pathway
negative regulation of SMAD protein import into nucleus
negative regulation of SMAD protein complex assembly
negative regulation of pathway-restricted SMAD protein phosphorylation
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