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          • Primary Antibodies ›
          • PMS2 Antibodies

          NeoBiotechnologies

          PMS2 (Postmeiotic Segregation Increased 2) Recombinant Rabbit Monoclonal Antibody (PMS2, 4373R)

          View all (42) PMS2 antibodies

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          Cite PMS2 (Postmeiotic Segregation Increased 2) Recombinant Rabbit Monoclonal Antibody (PMS2, 4373R)

          Additional Information:
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          • Antibody Testing Data (4)
          PMS2 (Postmeiotic Segregation Increased 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          PMS2 (Postmeiotic Segregation Increased 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          PMS2 (Postmeiotic Segregation Increased 2) Antibody (5395-RBM1-P1) in IHC (P)

          Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human colon carcinoma using PMS2 (Postmeiotic Segregation Increased 2) Recombinant Monoclonal Antibody (Product # 5395-RBM1-P1). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PMS2 (Postmeiotic Segregation Increased 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PMS2 (Postmeiotic Segregation Increased 2) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PMS2 (Postmeiotic Segregation Increased 2) Antibody in Peptide array (ARRAY)
          PMS2 (Postmeiotic Segregation Increased 2) Antibody in SDS-PAGE (SDS-PAGE)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          PMS2 (Postmeiotic Segregation Increased 2) Recombinant Rabbit Monoclonal Antibody (PMS2, 4373R)

          Product Details

          5395-RBM1-P1

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-2 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1-2 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          1-2 µg/mL
          -

          Flow Cytometry (Flow)

          1-2 µg/10^6 cells
          -

          Peptide Array (Array)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          PMS2, 4373R

          Immunogen

          A synthetic peptide corresponding to residues within aa1-100 of human PMS2
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          200 µg/mL

          Amount

          100 µg

          Purification

          Protein A/G

          Storage buffer

          PBS, pH 7.4, with 0.05% BSA

          Contains

          0.05% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

          Target Information

          PMS1 protein homologue 2 (PMS2) is a DNA mismatch repair protein. Defects in PMS2 are a cause of hereditary non-polyposis cancer (HNPCC). Human PMS2 is an amino acid protein of 862 amino acids.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: DNA mismatch repair protein PMS2; H_DJ0042M02.9; PMS1 homolog 2, mismatch repair protein; PMS1 protein homolog 2; PMS2 postmeiotic segregation increased 2; similar to S. cerevisiae PMS1 Swiss-Prot Accession Number P14242, S. cerevisiae MLH1 GenBank Accession Number U07187, E. coli MUTL Swiss-Prot Accession Number P23367, Salmonella typhimurium MUTL Swiss-Prot Accession Number P14161, Streptococcus pneumoniae ; unnamed protein product

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          Gene Aliases: HNPCC4; LYNCH4; MLH4; MMRCS4; PMS-2; PMSL2

          View more View less

          UniProt ID: (Human) P54278

          View more View less

          Entrez Gene ID: (Human) 5395

          View more View less

          Function(s)
          DNA binding single-stranded DNA binding endonuclease activity protein binding ATP binding ATPase activity mismatched DNA binding single base insertion or deletion binding MutSalpha complex binding ATP-dependent DNA damage sensor activity
          Process(es)
          meiotic mismatch repair mismatch repair response to xenobiotic stimulus somatic hypermutation of immunoglobulin genes positive regulation of isotype switching to IgA isotypes positive regulation of isotype switching to IgG isotypes
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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