Abnova

POLS Monoclonal Antibody (2F8)

Name: POLS Monoclonal Antibody (2F8)
Brand: Abnova
SKU: H00011044-M01
Price: 6404.00 CNY
Availability: InStock

查看其他5个TRF4-1抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

图: 1 / 1

POLS Antibody (H00011044-M01) in WB

Western blot analysis of POLS over-expressed 293 cell line, cotransfected with POLS Validated Chimera RNAi. Blot probed with POLS monoclonal antibody (M01), clone 2F8. GAPDH ( 36.1 kDa ) used as specificity and loading control.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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产品信息

H00011044-M01

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

功能检测 (Functional)

1-5 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b, kappa

分类

Monoclonal

类型

Antibody

克隆号

2F8

抗原

POLS (NP_008930, 2 a.a. approximately 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

100 µg

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with RNAi Knockdown.

Immunogen sequence: SPCPEEAAMR REVVKRIETV VKDLWPTADV QIFGSFSTGL YLPTSDIDLV VFGKWERPPL QLLEQALRKH NVAEPCSIKV LDKATVPIIK LTDQETEVKV DISFNMETG

靶标信息

TRF4-1 is a nuclear protein whose expression is cell cycle-regulated at a post-transcriptional level. Two genes, TRF4-1 and TRF4-2, belonging to this family have been identified. TRF4 is also required to maintain a different aspect of higher order chromosome structure, sister chromatid cohesion.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: DNA polymerase kappa; DNA polymerase sigma; non-canonical poly(A) polymerase; non-canonical poly(A) RNA polymerase PAPD7; PAP-associated domain-containing protein 7; poly(A) RNA polymerase D7, non-canonical; polymerase (DNA directed) sigma; terminal guanylyltransferase; terminal uridylyltransferase 5; topoisomerase-related function protein 4-1; TRAMP-like complex polyadenylate polymerase; Trf4-1p; unnamed protein product

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基因别名: LAK-1; LAK1; PAPD7; POLK; POLS; TRF4; TRF4-1; TRF41; TUTASE5

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UniProt ID: (Human) Q5XG87

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Entrez Gene ID: (Human) 11044

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功能

protein binding SMC family protein binding adenylyltransferase activity guanylyltransferase activity RNA adenylyltransferase activity

参与通路

double-strand break repair RNA catabolic process sister chromatid cohesion mitotic chromosome condensation response to xenobiotic stimulus RNA 3'-end processing polyadenylation-dependent ncRNA catabolic process negative regulation of nuclear-transcribed mRNA poly(A) tail shortening positive regulation of 3'-UTR-mediated mRNA stabilization