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Invitrogen
POU2F3 Polyclonal Antibody
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产品信息
PA5-139916
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human POU2F3. Recombinant protein control fragment (Product #RP-109346).
偶联物
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: PVHSTMPGTV TSSCSPGNNS RPSSPGSGLH ASSPTASQNN SKAAVNSASS FNSSGSWYRW NHSTYL
Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 90%.
靶标信息
POU2F3 (POU class 2 homeobox 3) is a transcription factor that regulates gene expression by binding specific DNA sequences through its POU domain. It is best known for controlling the development and identity of tuft cells in epithelial tissues and has emerging roles in certain cancers, particularly tuft cell-like carcinomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Oct-11; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF-11; POU domain transcription factor OCT11a; POU domain, class 2, transcription factor 3; Skn-1a, Epoc-1; Transcription factor PLA-1; Transcription factor Skn-1; unnamed protein product
基因别名: Epoc-1; OCT-11; OCT11; OTF-11; OTF11; PLA-1; PLA1; POU2F3; Skn-1a
UniProt ID: (Human) Q9UKI9
Entrez Gene ID: (Human) 25833
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
epidermis development
cell differentiation
keratinocyte differentiation
wound healing
negative regulation by host of viral transcription
positive regulation of transcription from RNA polymerase II promoter
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