Invitrogen

POU2F3 Polyclonal Antibody

Name: POU2F3 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-19303

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说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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POU2F3 Antibody (PA5-19303) in WB

Western blot analysis of PLA1 using PLA1 Polyclonal Antibody (Product # PA5-19303) (2 µg/mL) in staining of HEK293 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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产品信息

PA5-19303

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-3 µg/mL

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide sequence (EPHLEASQHLPVPKH) corresponding to the internal amino acids of POU2F3 (aa 161-176).

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

100 µg

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_10978767

产品详细信息

This antibody is predicted to react with bovine, canine and rat based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

靶标信息

POU2F3 (POU class 2 homeobox 3) is a transcription factor that regulates gene expression by binding specific DNA sequences through its POU domain. It is best known for controlling the development and identity of tuft cells in epithelial tissues and has emerging roles in certain cancers, particularly tuft cell-like carcinomas.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Oct-11; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF-11; POU domain transcription factor OCT11a; POU domain, class 2, transcription factor 3; Skn-1a, Epoc-1; Transcription factor PLA-1; Transcription factor Skn-1; unnamed protein product

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基因别名: Epoc-1; OCT-11; OCT11; OTF-11; OTF11; PLA-1; PLA1; POU2F3; Skn-1a

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UniProt ID: (Human) Q9UKI9

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Entrez Gene ID: (Human) 25833

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功能

RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding identical protein binding sequence-specific DNA binding sequence-specific double-stranded DNA binding

参与通路

regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter epidermis development cell differentiation keratinocyte differentiation wound healing negative regulation by host of viral transcription positive regulation of transcription from RNA polymerase II promoter