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Invitrogen
POU2F3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-38028
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
17 amino acid peptide near the carboxy terminus of human POU2F3
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A recommended positive control is SK-N-SH cell lysate.
At least two isoforms are known to exist; this antibody will recognize both isoforms. POU2F3 antibody is not expected to cross-react with other members of the POU domain class 2 family.
Target Information
POU2F3 (POU class 2 homeobox 3) is a transcription factor that regulates gene expression by binding specific DNA sequences through its POU domain. It is best known for controlling the development and identity of tuft cells in epithelial tissues and has emerging roles in certain cancers, particularly tuft cell-like carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Epoc-1; Oct-11; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF-11; POU domain, class 2, transcription factor 3; Rov 1 pou-homeodomain protein; Transcription factor Skn-1
Gene Aliases: Epoc-1; Epoc1; Oct-11a; Oct11; Otf-11; Otf11; Pou2f3; Skin; Skin-1a; Skn-1; Skn-1a; Skn-li; Skn1
UniProt ID: (Rat) P42571, (Mouse) P31362
Entrez Gene ID: (Rat) 116544, (Mouse) 18988
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
protein dimerization activity
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
epidermis development
keratinocyte differentiation
wound healing
negative regulation by host of viral transcription
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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