Search
Invitrogen
POU3F2 Monoclonal Antibody (CL6228)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 8
POU3F2 Antibody (MA5-35032) in ICC/IF
Immunofluorecent analysis of POU3F2 in U-251 cells using POU3F2 Monoclonal Antibody (CL6228) (Product # MA5-35032). Staining shows specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-35032
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CL6228
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ASNHYSLLTS SASIVHAEPP GGMQQGAGGY REAQSLVQGD YGALQSNGHP
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
靶标信息
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 7-Oct; brain-2; brain-2 class III POU-domain protein; brain-specific homeobox/POU domain protein 2; nervous system-specific octamer-binding transcription factor N-Oct-3; octamer-binding protein 7; octamer-binding transcription factor 7; unnamed protein product
基因别名: 9430075J19Rik; A230098E07Rik; Brn-2; BRN2; N-Oct3; oct-7; OCT7; OTF-7; OTF7; POUF3
UniProt ID: (Human) P20265, (Mouse) P31360
Entrez Gene ID: (Human) 5454, (Mouse) 18992
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
HMG box domain binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
brain development
positive regulation of cell proliferation
negative regulation of gene expression
neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
neuron fate commitment
neuron fate specification
neuron development
epidermis development
astrocyte development
Schwann cell development
cerebral cortex radially oriented cell migration
forebrain ventricular zone progenitor cell division
hypothalamus cell differentiation
neurohypophysis development
myelination in peripheral nervous system
positive regulation of multicellular organism growth
regulation of cell differentiation
regulation of axonogenesis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
