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Abnova
POU4F3 Polyclonal Antibody, MaxPab™
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POU4F3 Antibody (H00005459-B01P) in WB
Western Blot analysis of POU4F3 expression in transfected 293T cell line (H00005459-T01) by POU4F3 MaxPab polyclonal antibody.
Lane 1: POU4F3 transfected lysate(37.18 KDa).
Lane 2: Non-transfected lysate.
Lane 1: POU4F3 transfected lysate(37.18 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00005459-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
POU4F3 (NP_002691.1, 1 a.a. approximately 338 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MMAMNSKQPF GMHPVLQEPK FSSLHSGSEA MRRVCLPAPQ LQGNIFGSFD ESLLARAEAL AAVDIVSHGK NHPFKPDATY HTMSSVPCTS TSSTVPISHP AALTSHPHHA VHQGLEGDLL EHISPTLSVS GLGAPEHSVM PAQIHPHHLG AMGHLHQAMG MSHPHTVAPH SAMPACLSDV ESDPRELEAF AERFKQRRIK LGVTQADVGA ALANLKIPGV GSLSQSTICR FESLTLSHNN MIALKPVLQA WLEEAEAAYR EKNSKPELFN GSERKRKRTS IAAPEKRSLE AYFAIQPRPS SEKIAAIAEK LDLKKNVVRV WFCNQRQKQK RMKYSAVH
靶标信息
POU4F3 encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brain-3C; Brain-specific homeobox/POU domain protein 3C; brn-3C; MGC138412; POU domain, class 4, transcription factor 3
基因别名: BRN3C; DFNA15; POU4F3
UniProt ID: (Human) Q15319
Entrez Gene ID: (Human) 5459
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription from RNA polymerase II promoter
visual perception
sensory perception of sound
vestibulocochlear nerve development
retinal ganglion cell axon guidance
inner ear morphogenesis
auditory receptor cell differentiation
positive regulation of transcription from RNA polymerase II promoter
axon extension
neuromuscular process controlling balance
neuron apoptotic process
