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Invitrogen
PP2A alpha/beta Polyclonal Antibody
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PP2A alpha/beta Antibody (PA5-78119) in IHC (P)
PP2A alpha/beta Polyclonal Antibody detects PP2A alpha + PP2A beta protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. PP2A alpha + PP2A beta stained by PP2A alpha/beta Polyclonal Antibody (Product # PA5-78119) diluted at 1:1,000. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-78119
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PP2A alpha + PP2A beta. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.11 mg/mL
规格
111 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Zebrafish (100%), Pig (100%), Rabbit (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PP2A-alpha; PP2A-beta; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, alpha isoform; protein phosphatase 2, catalytic subunit, beta isoform; protein phosphatase 2A catalytic alpha subunit; protein phosphatase 2a, catalytic subunit, alpha isoform; protein phosphatase 2a, catalytic subunit, beta isoform; protein phosphatase-2A-alpha; protein phosphatase-2A-beta; Replication protein C; RP C; RP-C; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
基因别名: AI115466; D8Ertd766e; PP2A; Pp2a1; Pp2a2; PP2Ac; PPP2CA; PPP2CB; R75353
UniProt ID: (Mouse) P63330, (Rat) P63331, (Rat) P62716, (Mouse) P62715
Entrez Gene ID: (Mouse) 19052, (Rat) 24672, (Rat) 24673, (Mouse) 19053
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein binding
protein C-terminus binding
hydrolase activity
enzyme binding
protein kinase binding
protein phosphatase binding
protein domain specific binding
protein complex binding
protein kinase B binding
ion channel binding
metal ion binding
protein dimerization activity
tau protein binding
GABA receptor binding
protein phosphatase 2A binding
protein antigen binding
protein heterodimerization activity
protein phosphatase
negative regulation of transcription from RNA polymerase II promoter
regulation of protein phosphorylation
negative regulation of protein phosphorylation
protein dephosphorylation
mesoderm development
regulation of receptor activity
negative regulation of epithelial to mesenchymal transition
regulation of protein autophosphorylation
positive regulation of protein phosphatase type 2A activity
positive regulation of protein dephosphorylation
regulation of protein catabolic process
negative regulation of transcription factor import into nucleus
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
meiotic cell cycle
regulation of cell cycle
protein heterotrimerization
cellular response to glucose stimulus
positive regulation of protein serine/threonine kinase activity
negative regulation of calcium ion transmembrane transporter activity
cardiac ventricle development
heart development
cellular response to insulin stimulus
cellular response to calcium ion
cellular response to cytokine stimulus
cellular response to ethanol
cellular response to follicle-stimulating hormone stimulus
cellular response to steroid hormone stimulus
apoptotic mitochondrial changes
regulation of gene expression
response to endoplasmic reticulum stress
response to hydrogen peroxide
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of Ras protein signal transduction
response to antibiotic
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