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A suggested positive control is Raji cell lysate.
PA5-20865 can be used with blocking peptide PEP-0979.
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ46512; FLJ90191; Lipid phosphatase-related protein-B; LPRP-B; MGC15483; PA-PSP; phosphatidic acid phosphatase type 2 domain containing 2; Phosphatidic acid phosphatase type 2 domain-containing protein 2; Phospholipid phosphatase 6; polyisoprenoid diphosphate phosphatase type 1; Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6; PPAP2 domain-containing protein 2; Presqualene diphosphate phosphatase; RP11-6J24.2; Type 1 polyisoprenoid diphosphate phosphatase
基因别名: 4932443D16Rik; bA6J24.6; PDP1; PLPP6; PPAPDC2; PSDP
UniProt ID: (Human) Q8IY26, (Mouse) Q9D4F2, (Rat) Q66H88
Entrez Gene ID: (Human) 403313, (Mouse) 74411, (Rat) 619549
分子生物学功能: phosphatase