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Abnova
PPARBP Monoclonal Antibody (2A2)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00005469-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2A2
抗原
PPARBP (NP_004765, 1391 a.a. approximately 1490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.37 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: KIIISKHDGG SPSIKAKVTL QKPGESSGEG LRPQMASSKN YGSPLISGST PKHERGSPSH SKSPAYTPQN LDSESESGSS IAEKSYQNSP SSDDGIRPLP
靶标信息
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activator-recruited cofactor 205 kDa component; ARC205; nuclear receptor interacting protein; p53 regulatory protein RB18A; peroxisome proliferator-activated receptor-binding protein; PPAR-binding protein; PPARG binding protein; PPRB; thyroid hormone receptor-associated protein complex 220 kDa component; thyroid hormone receptor-associated protein complex component TRAP220; thyroid receptor interacting protein 2; TR-interacting protein 2; TRIP-2; unnamed protein product; vitamin D receptor-interacting protein 230 kD; vitamin D receptor-interacting protein complex component DRIP205
基因别名: CRSP1; CRSP200; DRIP205; DRIP230; PBP; PPARBP; PPARGBP; RB18A; TRAP220; TRIP2
UniProt ID: (Human) Q15648
Entrez Gene ID: (Human) 5469
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription coactivator binding
DNA binding
chromatin binding
transcription cofactor activity
transcription coactivator activity
transcription corepressor activity
protein binding
ligand-dependent nuclear receptor binding
estrogen receptor binding
chromatin DNA binding
histone acetyltransferase binding
vitamin D receptor binding
retinoic acid receptor binding
peroxisome proliferator activated receptor binding
macromolecular complex binding
thyroid hormone receptor binding
LBD domain binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
ubiquitin protein ligase activity
general transcription initiation factor binding
DNA-binding transcription factor binding
promoter-specific chromatin binding
negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
angiogenesis
lens development in camera-type eye
thyroid hormone mediated signaling pathway
ventricular trabecula myocardium morphogenesis
retinal pigment epithelium development
regulation of transcription from RNA polymerase II promoter
androgen biosynthetic process
positive regulation of gene expression
negative regulation of keratinocyte proliferation
protein ubiquitination
keratinocyte differentiation
intracellular steroid hormone receptor signaling pathway
positive regulation of transcription elongation from RNA polymerase II promoter
megakaryocyte development
mRNA transcription from RNA polymerase II promoter
negative regulation of apoptotic process
fat cell differentiation
positive regulation of keratinocyte differentiation
positive regulation of erythrocyte differentiation
negative regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
erythrocyte development
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
cellular response to epidermal growth factor stimulus
cellular response to steroid hormone stimulus
cellular response to thyroid hormone stimulus
regulation of RNA biosynthetic process
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